Encorafenib (LGX818)
Product Number :
CAS No. :
Brand :
Molecular formula :
Molecular weight :
Properties :
| Item Number | Pack Size | Purity/Level | Delivery period | Price | Quantity |
|---|---|---|---|---|---|
| YB563427-10mg | 10mg | 99% | In Stock | ||
| YB563427-25mg | 25mg | 99% | In Stock |
Basic Information
| English name | Encorafenib (LGX818) |
|---|---|
| Alternative name | 恩考替尼 | 康奈非尼 | 恩拉非尼 | 恩哥拉非尼 | BRAFV600E抑制剂(LGX818) | (S)-[1-[[4-[3-[5-氯-2-氟-3-(甲基磺酰胺基)苯基]-1-异丙基-1H-吡唑-4-基]嘧啶-2-基]氨基]丙-2-基]氨基甲酸甲酯 | (S)-[1-[[4-[3-[5-氯-2-氟-3-(甲基磺酰氨基)苯基]-1-异丙基-1H-吡唑-4-基]嘧啶-2-基]氨基]丙-2-基]氨基甲酸叔丁酯 |
| Cas No. | 1269440-17-6 |
| Precise molecular weight | 539.15178 |
| Smiles | C[C@@H](CNC1=NC=CC(C2=CN(C(C)C)N=C2C2=C(F)C(NS(=O)(=O)C)=CC(Cl)=C2)=N1)NC(=O)OC |
Safety Information
| Density | 1.45±0.1 g/cm3(Predicted) |
|---|---|
| Key Words | Warning |
| Melting point | 184-185°C |
| Transportation requirements | 低温冰袋运输 |
| Characteristics | * |
| Purpose | Encorafenib (LGX818)是高效的RAF抑制剂，作用于表达B-RAF(V600E)的细胞，具有选择性的抗增殖和凋亡活性，EC50为4 nM。Phase 3。 |
| Water solubility | 可溶于DMSO（少许）、甲醇（少许） |
| Symbol | GHS07 |
| Storage requirements | -20°C储存 |
Product Details
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